To init in boot mode: -Press S1 and S2 -Release S1 -Release S2 The device should resart in USB Bootloader # windows dfu-util.exe -a 0 -i 0 -s 0x08000000:leave -D firmware.bin # linux dfu-util -a 0 -i 0 -s 0x08000000:leave -D firmware.bin