Integrated Master’s degree in Biological Engineering at IST
PD-FCT AIM project is entitled “Microfluidic bioreactors for cascade enzymatic reactions” and will take place at INESC-MN and IBB. The thesis will be supervised by Professor João Pedro Conde (INESC-MN and Department of Bioengineering) and co-supervised by Professor Pedro Fernandes (IBB). His doctoral program started on the 22nd of September 2016.
The objective of this doctoral project is to study the design, implementation and characterization of microfluidic microreactors for complex cascade reactions using a series of enzymatic and chemical reactions.
Two potential applications will be studied: (i) biosensing of metabolites (in plants, animals and humans); and (ii) screening of production conditions for high value added biotechnological products.
In addition, the integration of additional processing modules to the microfluidic microreactor will be studied: (i) sample preparation; and (ii) downstream separation.
- Attending the Sensors, Signals and Instrumentation course at IST;
- Developing a biochemical POC assay for the monitoring of grape health;
- Developing microfluidic bioreactors for enzymatic synthesis;
- Ongoing collaboration with FFUL on the development of a microfluidic cell culture platform;
- Attended a pressure sensor microfabrication course: Summer School at the University of Applied Sciences Kaiserslautern, Germany;
- Development of microfluidic bioreactors for the cultivation of yeast;
- Completed the courses of Bioentrepreneurship, Basic Doctoral training and Teaching and scientific communication course (IST).
- Bras, Eduardo JS, et al. “A multiplexed microfluidic toolbox for the rapid optimization of affinity-driven partition in aqueous two phase systems.” Journal of Chromatography A 1515 (2017): 252-259.
- Brás, Eduardo JS, et al. “A microfluidic platform for physical entrapment of yeast cells with continuous production of invertase.” Journal of Chemical Technology and Biotechnology 92.2 (2017): 334-341.
- Poster Presentation at the Microbiotec conference entitled: “Affinity driven aqueous-two phase extraction of antibodies: a microfluidic approach.”; 7/12-9/12/2017
- Oral Presentation at the Anything But Conventional Chromatography Workshop Organized by ESBES, entilted: “Rapid and multiplexed screening of aqueous two-phase systems for the affinity driven partition of biopharmaceuticals using a microfluidic toolbox.”, 24/11/2017
- Academic Excellence Diploma for the year 2014/2015