Isabel Sá-Correia

(Full Professor) *

Alternative Pages: Google Scholar; Research ID; iBB webpage; IST webpage

Status at iBB - Institute for Bioengineering and Biosciences:  

Activities at the Department of Bioengineering (DBE):

  • Full Professor at the Department of Bioengineering

  • Vice-president of the Department of Bioengineering

  • Coordinator of the Scientific and Pedagogic Area of Biological Sciences

  • Coordinator of the Ph.D programme in Biotechnology and Biosciences

  • Director of the FCT funded PhD program BIOTECnico in Biotechnology and Biosciences

  • Coordinator of the joint Master's program in Microbiology, IST in collaboration with Faculty of Sciences, Medicine and Veterinary Medicine of the Universidade de Lisboa

  • Directive Board Member of the FCT funded PhD program in Applied and Environmental Microbiology (AEM)

  • Coordinator of the Master Course in Biotechnology

  • Coordinator of the Erasmus Mundus Master's Programme in Systems Biology euSYSBIO (IST in collaboration with KTH, Stockholm and Finland's Aalto University)

Education and Degrees:

  • Graduation in Chemical Engineering, Instituto Superior Técnico (IST) - Technical University of Lisbon, 1975

  • Post-Graduation in Biological Engineering (Molecular Biology), New University of Lisbon / Gulbenkian Institute of Science, 1980

  • Ph.D. in Chemical Engineering / Biotechnology (Microbiology; thesis work carried out in the Microbiology Laboratory of Gulbenkian Institute of Science in the field of Yeas Biology, adviser: Prof. N. van Uden), IST, 1984

  • Post-doctoral training, as Fulbright Visiting Assistant Professor, at the University of Illinois at Chicago (USA), Medical Center (with Prof. A.M. Chakrabarty; Molecular Microbiology of Pseudomonas), 1985/86

  • "Agregação" (Habilitation) in Chemical Engineering (Biotechnology/Biological Sciences), IST, 1992

Positions:

  • Full Professor (since 1995) at the Department of Chemical and Biological Engineering (DEQB) and later at the Department of Bioengineering

  • Member of the General Council, Universidade de Lisboa (since 2013)

  • Member of the Scientific Board of IST (since 2009)

  • Member of the Directive Board of iBB (since 2015).

  • Scientific Coordinator of the Biological Sciences Research Group (since 1993)

  • Associate Professor, DEQB-IST (1989-1995)

  • Visiting Assistant Professor, University of Illinois at Chicago (Medical Center) (1985-1986)

  • Assistant Professor, IST (1984-1989)

  • Teaching Assistant, IST and Ph.D. Student at the Laboratory of Microbiology, Gulbenkian Institute of Science (1975-1989)

Other Activities:

  • Councillor, CNE-Conselho Nacional de Educação - National Council of Education (2015-2019)

  • Coordinator and/or Member of the evaluation panel "Biochemistry and Biotechnology_University Education" of the Agency for the Evaluation and Accreditation of Higher Education (A3ES, Portugal).

  • Editorial Board Member of Applied & Environmental Microbiology (1997-2006), FEMS Yeast Research (since 2007), OMICS: a Journal of Integrative Biology (since 2010), Journal of Biomedicine and Biotechnology (since 2008), International Journal of Microbiology (2008-2013) and Microbial Cell (since 2013)

  • President of the Portuguese Society of Microbiology (since January 2009)

  • FEMS (Federation of European Microbiology Societies) Council delegate (since 2009)

  • Vice-President of the Portuguese Society of Biotechnology (1993-2003)

Area of scientific activity:

Microbial Sciences (Molecular and Cellular Microbiology, Biochemistry, Physiological Genomics)

Domain of specialization:

Microbiology and Physiological Genomics (Molecular and Cellular Biology, Biochemistry and Functional Genomics of Yeast and Pseudomonas-like bacteria, in particular bacteria of the Burkholderia cepacia complex; Yeast Toxicogenomics)

Research interests:

Stress Response and Tolerance in Yeasts (gene and genomic expression regulation under stress; drug/xenobiotic efflux pumps; design and engineering of more robust strains for biotechnology; control of spoilage yeast).

Pseudomonas and Pseudomonas-like bacteria biology and biotechnology. Burkholderia cepacia complex bacteria in cystic fibrosis: epidemiology, adaptive evolution during long term infection and virulence determinants.

 

Selected publications:

Edition of Books:

I. Sá-Correia, M.C. Teixeira, N.P. Mira, "Book of Abstracts - PYFF6 - 6th Conference on Physiology of Yeasts and Filamentous Fungi", 2016 (ISBN: 978-989-20-6736-0)

Book chapters:

M.C. Teixeira, P.T.Monteiro, I. Sá-Correia, "Predicting gene and genomic regulation in Saccharomyces cerevisiae, using the YEASTRACT database: a step by step guided analysis", In: Methods in Molecular Biology - Yeast Functional Genomics (Frederic Devaux, Ed), Springer, vol. 1361, 391-404, 2016.

I. Sá-Correia, S.C. dos Santos, A. Madeira Burkholderia Proteomics: methodologies, challenges, and applications, In: Burkholderia: From Genomes to Functions (ed. Tom Coenye & 'Eshwar Mahenthiralingam), Horizon Press, 2014.

I. Sá-Correia,  J.F Guerreiro, M.C. Loureiro-Dias, C. Leão, M. Côrte-Real, ZYGOSACCHAROMYCES In: Encyclopedia of Food Microbiology 2nd Edition, edited by Carl Batt & Mary Lou Tortorello, 2014.

N.P. Mira, M.C. Teixeira, I. Sá-Correia, "Characterization of complex regulatory networks and identification of promoter regulatory elements in yeast: in silico and wet-lab", In: Methods in Molecular Biology - Transcriptional Regulation: Methods and Protocols (Vancura A., Ed), Springer, vol. 809, 27-48, 2012.

T.R. Cabrito, E. Remy, M.C. Teixeira, P. Duque, I. Sá-Correia, "Resistance to herbicides in the model organisms Saccharomyces cerevisiae and Arabidopsis thaliana: the involvement of multidrug resistance transporters", In: Herbicides and Environment (Kortekamp A, Ed), INTECH, Vienna, Austria, 623-640, 2011

T.R. Cabrito, M.C. Teixeira, I. Sá-Correia, “Global adaptive response and resistance to agricultural fungicides: lessons from yeast and phytopathogenic fungi” In: Fungicides: Chemistry, Environmental Impact and Health Effects (Columbus F, Ed), Nova Publishers, New York, USA, p. 228-253 (ISBN: 978-1-60692-631-4).

A.M. Fialho, L.M. Moreira, A.T. Granja, K. Hoffmann, A. Popescu, I. Sá-Correia, "Biotechnology of the bacterial gellan gum: genes and enzymes of the biosynthetic pathway", In: A Portrait of State-of-the-Art Research at the Technical University, (M.S. Pereira, ed.), Springer, Dordrecht, The Netherlands, pp. 233-250, 2007

A.L. Oliveira, A.T. Freitas, I. Sá-Correia, "Bioinformatics: a new approach for the challenges of molecular biology", In: A Portrait of State-of-the-Art Research at the Technical University, (M.S. Pereira, ed.), Springer, Dordrecht, The Netherlands, pp. 295-309, 2007

I. Sá-Correia, M.C. Teixeira, "As complexas redes de regulação da expressão genética na levedura: abordagens à escala do genoma". In: O Mundo do RNA: Novos Desafios e Perspectivas Futuras (Cecília M. Arraiano, A.M. Fialho, eds), Lidel Edições Técnicas, Lisboa,  p. 223-242, 2007

I. Sá-Correia, L.M. Moreira and A. M. Fialho, "Engenharia Genética", In: Biotecnologia: Fundamentos e Aplicações, (M. Mota e N. Lima, eds.), Lidel Edições Técnicas, Lisboa, pp. 125-161, 2003

Papers:

2017

Bernardo, R., Cunha, D.V., Wang, C., Pereira, L., Silva, S., Salazar, S.B., Schroeder, M.S., Okamoto, M., Takahashi-Nakaguchi, A., Chibana, H., Aoyoama, T., Sá-Correia, I., Azeredo, J., Butler, G., Mira, N.P., "The CgHaa1-regulon mediates response and tolerance to acetic acid stress in the human pathogen Candida glabrata", G3: Genes, Genomes and Genetics, 7(1):1-18, 2017.

Godinho, C.P., Mira, N.P., Cabrito, T.R., Teixeira, M.C., Alasoo, K., Guerreiro, J. F., Sá-Correia, I., “Yeast response and tolerance to benzoic acid involves the Gcn4- and Stp1- regulated multidrug/multixenobiotic resistance transporter Tpo1”, Applied Microbiology and Biotechnology, doi: 10.1007/s00253-017-8277-6, in press.

Henriques, S.F., Mira, N.P., Sá-Correia, I., Genome-wide search for candidate genes for yeast robustness improvement against formic acid reveals novel susceptibility (Trk1 and positive regulators) and resistance (Haa1-regulon) determinants, Biotechnology for Biofuels, in press.

Monteiro, P.T., Pais, P., Costa, C., Manna, S., Sá-Correia, I., Teixeira, M.C., 2017, "The PathoYeastract database: an information system for the analysis of gene and genomic transcription regulation in pathogenic yeasts", Nucleic Acids Research, 45(D1):D597-D603, 2017.

Palma, M., Dias, P.J., Roque, F.C., Luzia, L., Guerreiro, J.F., Sá-Correia, I., The Zygosaccharomyces bailii transcription factor Haa1 is required for acetic acid and copper stress responses suggesting subfunctionalization of the ancestral bifunctional protein Haa1/Cup2, BMC Genomics, in press.

Remy, E., Niño-González, M., Godinho, C., Cabrito, T.R., Teixeira, M.C., Sá-Correia, I., Duque, P., Heterologous expression of the yeast Tpo1p or Pdr5p membrane transporters in Arabidopsis confers plant xenobiotic tolerance, Scientific Reports, accepted for publication.

Swinnen, S.*, Henriques, S.C.F.*, Shrestha, R., Ho, P.W., Sá-Correia, I.**, Nevoigt, E.**, Improvement of yeast tolerance to acetic acid through Haa1 transcription factor engineering: towards the underlying mechanisms, Microbial Cell Factories, 16:7, 2017. (*co-first;**co-correspondent)  

2016

Araujo, R., Caramalho, R., Coutinho, C., Sá-Correia, I. SNaPBceBcon: a practical tool for identification and genotyping of Burkholderia cepacia and Burkholderia contaminansJ Clin Microbiol. 2:483-488, 2016.

Cabral, M.G., Pereira, M., Silva, Z., Iria, I., Coutinho, C., Lopes, A., Sá-Correia, I., Videira, P.A., Using dendritic cells to evaluate how Burkholderia cenocepacia clonal isolates from a chronically infected cystic fibrosis patient subvert immune functions, Medical Microbiology and Immunology, accepted for publication.

Ferreira, R.A., Roma-Rodrigues, C., Davies, L.C., Sá-Correia, I., Martins-Dias, S., A quantitative proteomic approach to highlight Phragmites sp. adaptation mechanisms to chemical stress induced by a textile dyeing pollutant, Science of The Total Environment, 573, 788, 2016.

Guerreiro J*, Muir A*, Ramachandran S, Thorner J**, Sá-Correia I**, Sphingolipid biosynthesis upregulation by TOR Complex 2-Ypk1 signaling during yeast adaptive response to acetic acid stress, Biochemical Journal 473(23): 4311-4325, 2016.(*co-first;**co-correspondent)

Guerreiro, J.F., Sampaio-Marques, B., Soares, R., Coelho, A.V., Leão, C., Ludovico, P., Sá-Correia, I., Mitochondrial proteomics of the acetic acid – induced programmed cell death response in a highly tolerant Zygosaccharomyces bailii – derived hybrid strain. Microbial Cell, 3(2): 65-78, 2016.

Maldonado, R., Sá-Correia, I., Valvano, M., Lipopolysaccharide modification in Gram-negative bacteria during chronic infection, FEMS Microbiology Reviews, 40(4): 480-493, 2016.

Moreira, A.S., Lourenço, A.B., Sá-Correia, I., 1H-NMR-based endometabolome profiles of Burkholderia cenocepacia clonal variants retrieved from a cystic fibrosis patient during chronic infection, Frontiers in Microbiology, 7:2024, 2016.

Moreira, A.S., Mil-Homens, D.*, Sousa, S.A.*, Coutinho, C.P.*, Pinto-de-Oliveira, A., Ramos, C.G., dos Santos, S.C., Fialho, A.M., Leitão, J.H., Sá-Correia, I., Variation of Burkholderia cenocepacia virulence potential during cystic fibrosis chronic lung infection. Virulence, doi:10.1080/21505594.2016.1237334 (in press).

2015

Coutinho, C.P., Barreto, C., Pereira, L., Lito, L., Melo Cristino, J., Sá-Correia, I. Incidence of Burkholderia contaminans at a cystic fibrosis centre with an unusually high representation of Burkholderia cepacia during 15 years of epidemiological surveillance. J Med Microbiol. 64(8):927-35, 2015.

Cullen, L., Weiser, R., Olszak, T., Maldonado, R.F., Moreira, A.S., Slachmuylders, L., Brackman, G., Paunova-Krasteva, T.S., Zarnowiec, P., Czerwonka, G., Reilly, J., Drevinek, P., Kaca, W., Melter, O., de Soyza, A., Perry, A., Winstanley, C., Stoitsova, S.R., Lavigne, R., Mahenthiralingam, E., Sá-Correia, I., Coenye, T., Drulis-Kawa, Z., Augustyniak, D., Valvano, M.A., McClean, S., "Phenotypic characterisation of an international Pseudomonas aeruginosa reference panel: Strains of cystic fibrosis origin show less in vivo virulence than non-CF strains", Microbiology, 161(10):1961-77, 2015.

dos Santos, S.C., Sá-Correia, I., "Yeast toxicogenomics: lessons from a eukaryotic cell model and cell factory", Current Opinion in Biotechnology 33:183–191.

Palma, P., Roque, F.C., Guerreiro, J., Mira, N.P., Queiroz, L., Sá-Correia, I., "Search for genes responsible for the remarkably high acetic acid tolerance of a Zygosaccharomyces bailii-derived interspecies hybrid strain", BMC Genomics, 16:1070.

Remy, E., Cabrito, T.R., Baptista, R.A., Teixeira M.C., Sá-Correia, I., Duque, P., "The Major Facilitator Superfamily transporter ZIFL2 modulates cesium and potassium homeostasis in Arabidopsis", Plant and Cell Physiology, 56 (1), 148-162.

Tyrrell J., Whelan N., Wright C., Sá-Correia I., McClean S., Thomas M., Callaghan M., "Investigation of the multifaceted iron acquisition strategies of Burkholderia cenocepacia", Biometals, in press, 28 (2), 367-380.

2014

Costa, C., Dias, P.J., Sá-Correia, I., Teixeira, M.C., "MFS multidrug transporters in pathogenic fungi: do they have real clinical impact?", Frontiers in Physiology, 5:197.

de Carvalho, J., Rodrigues, R.M.M., Tomé, B., Henriques, S.F., Mira, N.P., Sá-Correia, I., Ferreira, G.N.M., "Conformational and Mechanical changes of DNA upon transcription factor binding detected by a QCM and transmission line model", Analyst, 139(8): 1847-55.

Dias P.J., Sá-Correia I., "Phylogenetic and syntenic analyses of the 12-spanner drug:H(+) antiporter family 1 (DHA1) in pathogenic Candida species: evolution of MDR1 and FLU1 genes". Genomics, 104(1):45-57.

dos Santos, S.C., Teixeira, M.C., Dias, P.J., Sá-Correia, I., "MFS transporters required for multidrug/multixenobiotic (MD/MX) resistance in the model yeast: understanding their physiological function through post-genomic approaches", Frontiers in Physiology, 5:180.

Mira, N.P., Münsterkötter, M., Dias-Valada, F., Santos, J., Palma, M., Roque, F., Guerreiro, J., Rodrigues, F., Sousa, M.J., Leão, C., Guldener, U., Sá-Correia, I., "The genome sequence of the highly acetic acid-tolerant Zygosaccharomyces bailii derived interspecies hybrid strain ISA1307, isolated from a sparkling wine plant", DNA Research, 21(3):299-313.

Moreira, A.S., Coutinho, C.P., Avezedo, P., Lito, L., Melo-Cristino, J., Sá-Correia, I., "Burkholderia dolosa phenotypic variation during the decline in lung function of a cystic fibrosis patient along 5.5 years of chronic colonization", Journal of Medical Microbiology, 63: 594-601.

Pereira, F.B., Teixeira, M.C., Mira, N.P., Sá-Correia, I., Domingues, L., "Genome-wide screening of Saccharomyces cerevisiae genes required to foster tolerance towards industrial wheat straw hydrolysates", Journal of Industrial Microbiology & Biotechnology, 41: 1753-61.

Remy, E., Cabrito, T.R., Batista, R.A., Hussein, M.A.M., Teixeira, M.C., Athanasiadis, A., Sá-Correia, I., Duque, P., "Intron Retention in the 5'UTR of the Novel ZIF2 Transporter Enhances Translation to Promote Zinc Tolerance in Arabidopsis", PLOS Genetics, 10(5): e1004375.

Rodrigues, R.M.M., de Carvalho, J., Henriques, S.F., Mira, N.P., Sá-Correia, I., Ferreira, G.N.M., "Transmission Line Model Analysis of Transcription Factors Binding to Oligoduplexes - Differentiation of the Effect of Single Nucleotide Modifications", Analyst, 139(16):3871-4.

Teixeira, M.C., Monteiro, P.T., Guerreiro, J.F., Gonçalves, J.P., Mira, N.P., dos Santos, S.C., Cabrito, T., Palma, M., Costa, C., Francisco, A.P., Madeira, S.C., Oliveira, A.L., Freitas, A.T., Sá-Correia, I., The YEASTRACT database: an upgraded information system for the analysis of gene and genomic transcription regulation in Saccharomyces cerevisiae, Nucleic Acids Research, 42: D161-D166.

2013

Costa, C., Pires, C., Cabrito, T.R., Renaudin, A., Ohno, M., Chibana, H., Sá-Correia, I., Teixeira, M.C., 2013, Candida glabrata drug:H+ antiporter CgQdr2 (ORF CAGL0G08624g) confers imidazole drug resistance, being activated by the CgPdr1 transcription factor, Antimicrobial Agents and Chemotherapy, 57(7):3159-67.

Costa, C., Henriques, A.S., Pires, C., Nunes, J., Ohno, M., Chibana, H., Sá-Correia, I., Teixeira, M.C., 2013, The dual role of Candida glabrata Drug:H+ Antiporter CgAqr1 (ORF CAGL0J09944g) in antifungal drug and acetic acid resistance, Frontiers in Microbiology, 4: 170.

De Soyza, A., Hall, A., Mahenthiralingam, E., Drevinek, P., Kaca, W., Drulis-Kawa, Z., Stoitsova, S., Toth, V., Coenye, T., Zlosnik, J., Burns, J., Sá-Correia, I., De Vos, D., Pirnay, J.P. Kidd, T., Reid, D., Manos, J., Klockgether, J., Wiehlmann, L., Tummler, B., McClean, S., Winstanley, C., Developing an international Pseudomonas aeruginosa reference panel, Microbiology Open, 2, 1010-23.

Dias, P.J., Sá-Correia, I., The drug:H+ antiporters of family 2 (DHA2), siderophore transporters (ARN) and glutathione:H+ antiporters (GEX) have a common evolutionary origin in hemiascomycete yeasts, BMC Genomics, 14: 901.

Di Lorenzo, F., Silipo, A., Lanzetta, R., Fazio, L.L., Paciello, I., Coutinho, C.P., Sá-Correia, I., Bernardini. M., Molinaro, A., 2013, Structural elucidation and biological activity of the lipooligosaccharide of a Burkholderia dolosa isolate from a cystic fibrosis patient. ChemBioChem, 14(9): 1105-15 .

Eusébio, N., Coutinho, C., Sá-Correia, I., Araújo, R., 2013, SNaPBcen: a novel and practical tool for genotyping Burkholderia cenocepacia, Journal of Clinical Microbiology, 51(8): 2646-53.

Lourenço, A.B., Roque, F.C., Teixeira, M.C., Ascenso, J.R., Sá-Correia, I., Quantitative 1H-NMR-metabolomics reveals extensive metabolic reprogramming and the effect of the aquaglyceroporin FPS1 in ethanol-stressed yeast cells, PLOS One, 8(2): e55439.

Madeira, A., dos Santos, A.C., Santos, P.M., Coutinho, C.P., Tyrrell, J., McClean, S., Callaghan, M., Sá-Correia, I., Proteomic profiling of Burkholderia cenocepacia clonal isolates with different virulence potential retrieved from a cystic fibrosis patient during chronic lung infection, PLOS ONE 8(12): e83065.

Remy, E., Cabrito, T.R., Baster, P., Batista, R.A., Teixeira, M.C., Friml, J., Sá-Correia, I., Duque, P., 2013, A Major Facilitator Superfamily Transporter Plays a Dual Role in Polar Auxin Transport and Drought Stress Tolerance in Arabidopsis, The Plant Cell, 25: 901-26.

2012

Palma, M., Madeira, S.C, Mendes-Ferreira, A., Sá-Correia, I., Impact of assimilable nitrogen availability in glucose uptake kinetics in Saccharomyces cerevisiae during alcoholic fermentation, Microbial Cell Factories, 11: 99.

Teixeira, M.C., Godinho, C.P., Cabrito, T.R., Mira, N.P., Sá-Correia, I., Increased expression of the yeast multidrug resistance ABC transporter Pdr18 leads to increased ethanol tolerance and ethanol production in high gravity alcoholic fermentation, Microbial Cell Factories, 11, 98.

Guerreiro, J.F., Mira, N.P., Sá-Correia, I., Adaptive response to acetic acid in the highly resistant yeast species Zygosaccharomyces bailii revealed by quantitative proteomics. PROTEOMICS, 12: 2303-18.

Madeira; A., da Silva; C.L., Dos Santos, F., Camafeita, E., Cabral, J.M.S., Sá-Correia, I.,  Human Mesenchymal Stem Cell Expression Program upon Extended Ex-Vivo Cultivation, as Revealed by 2-DE-Based Quantitative Proteomics. PLoS ONE, 7(8), e43523 .

dos Santos, S.C., Mira, N.P., Moreira, A.S., Sá-Correia, I., Quantitative- and phospho-proteomic analysis of the yeast response to the tyrosine kinase inhibitor imatinib. OMICS: A Journal of Integrative Biology, 16: 537-51.

dos Santos, S.C., Teixeira, M.C., Cabrito, T.R., Sá-Correia, I., Yeast Toxicogenomics: genome-wide responses to chemical stresses with impact in Environmental Health, Pharmacology and Biotechnology. Frontiers in Genetics, 3, 63.

Remy, E., Cabrito, T.R., Baptista, R., Teixeira, M.C., Sá-Correia, I., Duque, P., The Pht1;9 transporter mediates inorganic Pi acquisition by the Arabidopsis thaliana root during phosphorus starvation. The New Phytologist, 195, 356–371.

2011

Mira, N.P., Madeira, A., Moreira, A.S., Coutinho, A.P., Sá-Correia, I., Genomic expression analysis reveals strategies of Burkholderia cenocepacia to adapt to the airways of cystic fibrosis patients and antimicrobial therapy . PLOS One, 6(12), e28831.

Pereira, F.B., Guimarães, P.M.R, Gomes, D.G., Mira, N.P., Teixeira, M.C., Sá-Correia, I., Domingues, L., Identification of candidate genes for yeast engineering to improve bioethanol production in Very-High-Gravity and lignocellulosic biomass industrial fermentations. Biotechnology for Biofuels, 4, 57.

Coutinho, C.P., dos Santos, S.C., Madeira, A., Mira, N.P., Moreira, A.S., Sá-Correia, I., Long-term colonization of the cystic fibrosis lung by Burkholderia cepacia complex bacteria: epidemiology, clonal variation and genome-wide expression alterations. Frontiers in Cellular and Infection Microbiology, 1, 12.

dos Santos, S.C., Sá-Correia, I., A genome-wide screen identifies yeast genes required for protection against or enhanced cytotoxicity of the antimalarial drug quinine. Molecular Genetics and Genomics, 286(5-6), 333-46.

Gonçalves, J.P., Francisco, A.P., Mira, N.P., Teixeira, M.C., Sá-Correia, I., Oliveira, A.L., Madeira, S.C., TFRank: Network-based prioritization of regulatory associations underlying transcriptional responses. Bioinformatics, 27, 3149-3157.

Cabrito, T.R., Teixeira, M.C., Singh, A., Prasad, R., Sá-Correia, I., The yeast ABC transporter Pdr18 (ORF YNR070w) controls plasma membrane sterol composition, playing a role in multidrug resistance. Biochemical Journal, 440, 195-202.

Rocha, J., Popescu, A.O., Borges, P., Mil-Homens, D., Moreira, L.M., Sá-Correia, I., Fialho, A.M., Frazão, C., Burkholderia cenocepacia UDP-glucose dehydrogenase (BceC) structure and role of the Tyr10 in the final hydrolysis of UGDs thioester intermediate. Journal of Bacteriology, 193, 3978-87.

Monteiro, P.T., Dias, P.J., Ropers, D., Oliveira, A.L., Sá-Correia, I., Teixeira, M.C., Freitas, A.T., Qualitative modeling and formal verification of the FLR1 gene mancozeb response in Saccharomyces cerevisiae. IET Systems Biology, 5, 308-16.

Coutinho, C.P., de Carvalho, C.C.C.R., Madeira, A., Pinto-de-Oliveira, A., Sá-Correia, I., Burkholderia cenocepacia phenotypic clonal variation during three and a half years of residence in the lungs of a cystic fibrosis patient. Infection and Immunity, 79, 2950-2960.

Teixeira M.C., Mira N.P., Sá-Correia I., A genome-wide perspective on the response and tolerance to food-relevant stresses in Saccharomyces cerevisiae. Current Opinion in Biotechnology, 22, 150-156 (abstract).

Mira, N.P., Henriques, S., Keller, G., Teixeira, M.C., Matos, R., Arraiano, C., Winge, D.R., Sá-Correia, I., Identification of a DNA binding site for the transcription factor Haa1p, required for Saccharomyces cerevisiae response to acetic acid stress. Nucleic Acids Research, 16, 6898-907.

Madeira, A., Santos, P.M., Coutinho, C.P., Pinto-de-Oliveira, A., Sá-Correia, I., Quantitative proteomics (2-D-DIGE) reveals molecular strategies employed by Burkholderia cenocepacia to adapt to the airways of cystic fibrosis patients under antimicrobial therapy. PROTEOMICS, 11, 1313-28.

Teixeira, M.C., Cabrito, T.R., Hanif, Z.M., Vargas, R.C., Tenreiro, S., Sá-Correia, I., Yeast response and tolerance to polyamine toxicity involving the drug:H+ antiporter Qdr3 and the transcription factors Yap1 and Gcn4. Microbiology, 157, 945-956

Abdulrehman D., Monteiro P.T., Teixeira M.C., Mira N.P., Lourenço A.B., dos Santos S.C., Cabrito T.R., Francisco A., Madeira S.C., Santos R., Oliveira, A.L., Sá-Correia I., Freitas A. T., “YEASTRACT: Providing a programmatic access to curated transcriptional regulatory associations in Saccharomyces cerevisiae through a web services interface. Nucleic Acids Research, 39, D136-140

Lourenço A.B., Ascenso J.R., Sá-Correia I., Metabolic insights into the yeast response to propionic acid based on high resolution 1H NMR spectroscopy. Metabolomics, 7, 457-468.

2010

Sá-Correia I., Teixeira M.C., Two-dimensional Electrophoresis-based Expression Proteomics: a microbiologist’s perspective. Expert Reviews in Proteomics, 7(6), 943-953, 2010

Mira, N.P., Palma, M., Guerreiro, J., Sá-Correia I., Genome-wide identification of Saccharomyces cerevisiae genes required for tolerance to acetic acid. Microbial Cell Factories, 9:79 (abstract)

Dias J.P., Seret M.L., Goffeau A., Sá-Correia I., Baret P., “Evolution of the 12-spanner drug:H+ antiporter DHA1 family in hemiascomycete yeasts.” OMICS: A Journal of Integrative Biology, 14(6):701-10.

Mira, N.P., Teixeira, M.C., Sá-Correia, I., "Characterization of complex regulatory networks and identification of promoter regulatory elements in yeast: in silico and wet-lab", In: Methods in Molecular Biology - Transcriptional Regulation: Methods and Protocols (Springer Ed) (in press)

Teixeira M.C., Dias P.J., Monteiro P.T., Sala A., Oliveira A.L., Freitas A.T., Sá-Correia I., Refining current knowledge on the yeast FLR1 regulatory network by combined experimental and computational approaches. Molecular Biosystems, 6(12), 2471-2481

Mira N.P., Becker J.D., Sá-Correia I., Genomic expression program involving the Haa1p-regulon in Saccharomyces cerevisiae response to acetic acid. OMICS: a Journal of Integrative Biology, 14(5), 587-601, 2010 (abstract)

Mira N.P., Teixeira M.C., Sá-Correia I., Adaptive response and tolerance to weak acids in Saccharomyces cerevisiae : a genome-wide view. OMICS: a Journal of Integrative Biology, 14(5), 525-540, 2010 (abstract)

C. Roma-Rodrigues, P.M. Santos, D. Benndorf, E. Rapp, I. Sá-Correia, Response of Pseudomonas putida KT2440 to phenol at the level of membrane proteome, Journal of Proteomics, 73(8): 1461-1478

S. Madeira, M.C. Teixeira, I. Sá-Correia, A.L. Oliveira, “Identification of Regulatory Modules in Time Series Gene Expression Data using a Linear Time Biclustering  Algorithm”, IEEE/ACM Transactions on Computational Biology and Bioinformatics, 7: 153-165, 2010

J. Rocha, A.T. Granja, I. Sá-Correia, A.M. Fialho, C. Frazão, 2009, "Cloning, expression, crystallization and preliminary crystallographic studies of UgdG, and UDP-glucose dehydrogenase from Sphingomonas elodea ATCC 31461" Acta Crytallographica. Section F, Structural Biology and Crystallization Communications (in press)

M.C. Teixeira, L.R. Raposo, M. Palma, I. Sá-Correia, 2010, "Identification of genes required for maximal tolerance to high-glucose concentrations, as those present in industrial alcoholic fermentation media, through a chemogenomics approach", OMICS: A Journal of Integrative Biology, 14(2), 201-210, 2010

P.J. Dias, M.C. Teixeira, J.P. Telo, I. Sá-Correia, 2010, "Insights into the mechanisms of toxicity and tolerance to the agricultural fungicide mancozeb in yeast, as suggested by a chemogenomic approach", OMICS: A Journal of Integrative Biology, 14(2), 211-227, 2010

2009

P.M. Santos, I. Sá-Correia, 2009,  "Adaptation to β-myrcene catabolism in Pseudomonas sp. M1: an expression proteomics analysis", PROTEOMICS, 9, 5101–5111, 2009 (abstract)

S. C. dos Santos, S. Tenreiro, M. Palma, J. Becker and I. Sá-Correia, “Transcriptomic profiling of the yeast response to quinine evidenced a glucose limitation response attributable to drug-induced inhibition of glucose uptake”, Antimicrobial Agents and Chemotherapy , 53, 5213-5223, 2009 (abstract)

M.C. Teixeira, L.R. Raposo, N.P. Mira, A.B. Lourenço and I. Sá-Correia, "Genome-wide identification of genes required for maximal tolerance to ethanol in yeast: important role of FPS1", Appl. Environ. Microbiol., 75: 5761-5772, 2009

M.C. Teixeira, P.M. Santos, C. Rodrigues, I. Sá-Correia, “Teaching Expression Proteomics: from the wet-lab to the laptop”, Biochemistry and Molecular Biology Education, 37, 279-286, 2009

C.P. Coutinho, I. Sá-Correia, J.A. Lopes,  2009, "Use of Fourier transform infrared spectroscopy and chemometrics to discriminate clinical isolates of bacteria of the Burkholderia cepacia complex from different species and ribopatterns", Analytical and Bioanalytical Chemistry, 394(8); 2161-2171, 2009

T.R. Cabrito, M.C. Teixeira, A.A. Duarte, P. Duque, I. Sá-Correia, "Heterologous expression of a Tpo1 homolog from Arabidopsis thaliana confers resistance to the herbicide 2,4-D and other chemical stresses in yeast", Applied Microbiology and Biotechnology, 84, 927-936, 2009

S.C. Madeira, M.C. Teixeira, I. Sá-Correia and A.L. Oliveira, "Identification of Regulatory Modules in Time Series Gene Expression Data using a Linear Time Biclustering Algorithm", IEEE/ACM Transactions on Computational Biology and Bioinformatics, 21 Mar 2008.  IEEE Computer Society Digital Library. IEEE Computer Society, 22 March 2008 http://doi.ieeecomputersociety.org/10.1109/TCBB.2008.34.

S.C. dos Santos, I. Sá-Correia, Genome-wide identification of genes required for yeast growth under imatinib stress: vacuolar H+-ATPase function is an important target of this anticancer drug, OMICS: A Journal of Integrative Biology, 13: 185-198, 2009

V.M.F. Gonçalves, A. Reis, M.R.M. Domingues, J.A. Lopes-da-Silva, A.M. Fialho, L.M. Moreira, I. Sá-Correia, M.A. Coimbra, Structural analysis of gellans produced by Sphingomonas elodea strains by electrospray tandem mass spectrometry, Carbohydrate Polymers,  77, 10-19, 2009

N.P. Mira, A. Lourenço, A. Fernandes, J. Becker, I. Sa-Correia, The RIM101 pathway has a role in Saccharomyces cerevisiae adaptive response and resistance to propionic acid and other weak acids, FEMS Yeast Research,  9, 202-216, 2009 (abstract)

I. Sá-Correia, S.C. dos Santos, M.C. Teixeira, T.R. Cabrito, N.P. Mira, "Drug:H+ antiporters in chemical stress response in yeast". Trends in Microbiology, 17, 22-31, 2009 (abstract)

P.M. Santos, T. Simões, I. Sá-Correia, "Insights into yeast adaptive response to the agricultural fungicide mancozeb: a toxicoproteomics approach", PROTEOMICS, 19, 19, 657-670, 2009 (abstract)

2008

A.M. Fialho, L.M. Moreira, A.T. Granja, A.O. Popescu, K. Hoffmann, I. Sá-Correia,  Occurrence, production and applications of gellan: current state and perspectives. Appl Microbiol Biotechnol, 79, 889-900, 2008 (abstract)

M.C. Teixeira, P.J. Dias,  T. Simões, I. Sá-Correia. “Yeast adaptation to mancozeb involves the up-regulation of FLR1 under the coordinate control of Yap1, Rpn4, Pdr3 and Yrr1” Biochemical Biophysical Research Communications, 367, 249-255, 2008 (abstract)

P. Monteiro, N. Mendes, M.C. Teixeira, S. d'Orey, S. Tenreiro, N.P. Mira, H. Pais, A. Francisco, A. Carvalho, A.R. Lourenço, I. Sá-Correia, A.L. Oliveira, A.T. Freitas. "YEASTRACT-DISCOVERER: new tools to improve the analysis of transcriptional regulatory associations in Saccharomyces cerevisiae". Nucleic Acids Res. Database Issue 36: D132-D136, 2008 (abstract)

J.H. Leitão, S.A. Sousa, M.V. Cunha, M.J. Salgado, J. Melo-Cristino, M.C. Barreto and I. Sá-Correia. "Variation of the antimicrobial susceptibility profiles of Burkholderia cepacia complex clonal isolates obtained from chronically infected  cystic fibrosis patients: a five-year survey in the major Portuguese treatment center". European Journal of Clinical Microbiology & Infectious Diseases, 27, 1101-1111, 2008 (abstract)

2007

P.M. Santos, I. Sá-Correia (2007), "Characterization of the unique organization and co-regulation of a gene cluster required for phenol and benzene catabolism in Pseudomonas sp. M1".  Journal of Biotechnology, 131, 371-378, 2007  (abstract)

A.T. Granja, A. Popescu, A.R. Marques, I. Sá-Correia, A.M. Fialho, "Biochemical characterization and phylogenetic analysis of UDP-glucose dehydrogenase from the gellan gum producer Sphingomonas elodea ATCC  31461" Applied Microbiology and Biotechnology, 2007 (accepted for  publication)

S.A. Sousa, M. Ulrich, A. Bragonzi, M. Burke, D. Worlitzch, J.H. Leitão, C. Meisner, L. Eberl, I. Sá-Correia, G. Döring, "Virulence of Burkholderia cepacia complex strain in gp91phox-/- mice", Cellular Microbiology, 9, 2817-2825, 2007(in press) (abstract)

D. Aragão, A.M. Fialho, A.R. Marques, E.P. Mitchell, I. Sá-Correia, C. Frazão, "The complex of Sphingomonas elodea ATCC 31461 Glucose-1-phosphate uridylyltransferase with glucose-1-phosphate reveals a novel quaternary structure, unique among Nucleoside Diphosphate-sugar pyrophosphorylase members", Journal of Bacteriology, 189, 4520–4528, 2007 (abstract)

M.C. Teixeira, P. Duque, I. Sá-Correia "Environmental Genomics: mechanistic insights into toxicity of and resistance to the herbicide 2,4-D", Trends in Biotechnology, 25: 363-370, 2007 (abstract)

M.V. Cunha, A. Pinto-de-Oliveira, L. Meirinhos-Soares, M.J. Salgado, J. Melo-Cristino, S. Correia, C. Barreto, I. Sá-Correia "Exceptionally high representation of Burkholderia cepacia among B. cepacia complex isolates recovered from the Major Portuguese Cystic Fibrosis Center", Journal of Clinical Microbiology, 45, 1628–1633, 2007 (abstract)

P.M. Santos,  V. Roma, D. Benndorf, M. von Bergen, H. Harms, I. Sá-Correia (2007) "Mechanistic insights into the global response to phenol in the phenol-biodegrading strain Pseudomonas sp. M1, revealed by quantitative proteomics", OMICS: A Journal of Integrative Biology, 11:233-251, 2007 (abstract)

R.C. Vargas, R. García-Salcedo, S. Tenreiro, M.C. Teixeira , A.R. Fernandes, J. Ramos and I. Sá-Correia , "Saccharomyces cerevisiae multidrug resistance transporter Qdr2 is implicated in potassium uptake, providing a physiological advantage to quinidine-stressed cells" Eukaryotic Cell, 6, 134-142, 2007(abstract)

S.A. Sousa, L.M. Moreira, J. Wopperer, L. Eberl, I. Sá-Correia, J.H. Leitão, "The Burkholderia cepacia bceA gene encodes a protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities", Biochemical and Biophysical Research Communications, 353, 200-206, 2007 (abstract)

A.S. Ferreira, J.H. Leitão, S.A. Sousa, A.M. Cosme, I. Sá-Correia, L.M. Moreira "Functional Analysis of Burkholderia cepacia bceD and bceF Genes  Encoding a Phosphotyrosine Phosphatase and a Tyrosine Autokinase: Role in Exopolysaccharide Biosynthesis and Biofilm Formation", Applied and Environmental Microbiology, 73, 524-534, 2007 (abstract)

2006

M. Alenquer, S. Tenreiro, I. Sá-Correia. 2006. Adaptive response to the antimalarial drug artesunate in yeast involves Pdr1p/Pdr3p-mediated transcriptional activation of the resistance determinants TPO1 and PDR5. FEMS Yeast Research, 6, 1130-1139, 2006 (abstract)

T. Simões, N.P. Mira, A.R. Fernandes, I. Sá-Correia, "The SPI1 gene, encoding a glycosylphosphatidylinositol (GPI)-anchored cell wall protein, plays a prominent role in the development of yeast resistance to lipophilic weak acids food preservatives", Applied and Environmental Microbiology, 72, 7168-7175, 2006 (abstract)

N.D. Mendes, A.C. Casimiro, P.M. Santos, I. Sá-Correia , A.L. Oliveira, A.T. Freitas, “MUSA: A parameter free algorithm for the identification of biologically significant motifs”, Bioinformatics22, 2996-3002, 2006  (abstract)

M.C. Teixeira, P. Monteiro, P. Jain, S. Tenreiro, A.R. Fernandes, N.P. Mira, M. Alenquer, A.T. Freitas, A.L. Oliveira, I. Sá-Correia, "The YEASTRACT database: a tool for the analysis of transcriptional regulatory associations in Saccharomyces cerevisiae", Nucleic Acids Research, Database Issue, 34, D446-D451, 2006 (abstract)

D. Aragão, A.R. Marques, C. Frazão, F.J. Enguita, M.A. Carrondo, A.M. Fialho, I. Sá-Correia, E.P. Mitchell, "Cloning, expression, purification, crystallization and preliminary structure determination of glucose-1-phosphate uridylytransferase (UgpG) from Sphingomonas elodea ATCC 31461 bound to glucose-1-phosphate", Acta Crystallographica, F62, 930-934, 2006 (abstract)

M.C. Teixeira, A.R. Fernandes, N.P. Mira, J.D. Becker, I. Sá-Correia, "Early transcriptional response of Saccharomyces cerevisiae to stress imposed by the herbicide 2,4-dichlorophenoxyacetic acid", FEMS Yeast Research, 6, 230–248, 2006 (abstract)

2005

A.R. Fernandes, N.P. Mira, R.C. Vargas, I. Canelhas, I. Sá-Correia, “Saccharomyces cerevisiae adaptation to weak acids involves the transcription factor Haa1p and of Haa1p-regulated genes”, Biochemical and Biophysical Research Communications, 337, 95-103, 2005 (abstract)

P.A. Videira, A.P. Garcia, I. Sá-Correia, “Functional and topological analysis of the Burkholderia cenocepacia priming glucosyltransferase BceB, involved in the biosynthesis of the cepacian exopolysaccharide, Journal of Bacteriology, 187, 5013-5018, 2005 (abstract)

E. Silva, A.R. Marques, A.M. Fialho, A.T. Granja, I. Sá-Correia, “Proteins Encoded by Sphingomonas elodea ATCC 31461 rmlA and ugpG genes, involved in gellan gum biosynthesis, exhibit both dTDP- and UDP-Glucose pyrophosphorylase activities”, Applied and Environmental Microbiology, 71, 4703-4712, 2005 (abstract)

C.A. Viegas, M.G. Cabral, M.C. Teixeira, G. Neumann, H.J. Heipieper, I. Sá-Correia, Yeast adaptation to 2,4-dichlorophenoxyacetic acid involves increased membrane fatty acid saturation degree and decreased OLE1 transcription, Biochemical and Biophysical Research Communications, 330: 271-278, 2005

F. Strino, A. Nahmany, J. Rosen, G.J.L. Kemp, I. Sá-Correia, P-G Nyholm, "Conformation of the exo-polysaccharice fo Burkholderia cepacia predicted with molecular mechanics (MM3) using genetic algorithm search", Carbohydrate Research, 340, 1019-1024, 2005 (abstract)

M.C.Teixeira, P.M. Santos, A.R. Fernandes, I. Sá-Correia, "A proteome analysis of yeast responses to the herbicide 2,4-dichlorophenoxyacetic  acid", Proteomics, 5, 1889-1901, 2005 (abstract).

S. Tenreiro, R.C. Vargas, M.C. Teixeira, C. Magnani, I. Sá-Correia, "The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinat of resistance to quinidine, barban, cisplatin and bleomycin", Biochemical and Biophysical Research Communications, 327, 952-959, 2005.

2004

L.M. Moreira, K. Hoffmann, H. Albano, A. Becker, K. Niehaus and I. Sá-Correia, "The gellan gum biosynthetic  genes gelC and gel E encode two separate polypeptides homologous to the activator and the kinase domains of tyrosine autokinases", Journal of Molecular Microbiology and Biotechnology, 8, 43-57, 2004 (abstract)

M.C. Teixeira, J.P. Telo, N.F. Duarte, I. Sá-Correia , "The herbicide 2,4-dichlorophenoxyacetic acid induces the generation of free-radicals and associated oxidative stress responses in yeast", Biochemical and Biophysical Research Communications, 324, 1101-1107, 2004 (abstract)

M.V. Cunha, S.A. Sousa, J.H. Leitão, L.M. Moreira, P.A. Videira, I. Sá-Correia, "Studies on the involvement of the exopolysaccharide produced by cystic fibrosis-associated isolates of the Burkholderia cepacia complex in biofilm formation and in persistence of respiratory infections", Journal of Clinical Microbiology, 42, 3052-3058, 2004 (abstract)

P.M. Santos, D. Benndorf, I. Sá-Correia, "Insights in Pseudomonas putida KT2440 response to phenol-induced stress by quantitative proteomics" Proteomics, 4, 2640-2652, 2004 (abstract)

R.C. Vargas, S. Tenreiro, M.C. Teixeira, A.R. Fernandes, I. Sá-Correia, "Saccharomyces cerevisiae multidrug transport Qdr2p (Yil121wp): localization and function as a quinidine resistance determinant", Antimicrobial Agents and Chemotherapy, 48, 2531-2537, 2004 (abstract)

M.G. Cabral,  I. Sá-Correia, C.A. Viegas, "Adaptative responses in yeast to the herbicide 2-methyl-4-chlorophenoxyacetic acid at the level of intracellular pH homeostasis", Journal of Applied Microbiology, 96, 603-612, 2004 (abstract)

I. Sá-Correia, “Integrating metabolism and genomics”, Conference Report ASM, FEMS Yeast Research, 5, 307-311, 2004

E. Silva, A.M. Fialho, I. Sá-Correia, R.G. Burns, L.J. Shaw, "Combined bioaugmentation and biostimulation to clean-up soil contaminated with high concentrations of atrazine", Environmental Science and Technology, 38, 632-637, 2004 (abstract)

C. Papaefthimiou, M.G. Cabral, C. Mixailidou, C.A. Viegas, I. Sá-Correia, G. Theophilidis, "Comparison of two screening bioassays, based on the frog sciatic nerve and yeast cells, for the assessment of herbicide toxicity", Environmental Toxicology and Chemistry, 23, 1211-1218, 2004  (abstract)

2003

L.M. Moreira,  P.A. Videira, S.A. Sousa, J.H. Leitão, M.V. Cunha, I. Sá-Correia,  "Identification and physical organization  of the gene cluster involved in the biosynthesis of Burkholderia cepacia complex exopolysaccharide", Biochemical and Biophysical Research Communications, 312, 323-333, 2003 (abstract)

A.R. Fernandes, P.J. Durão, P.M. Santos, I. Sá-Correia, "Activation and significance of vacuolar H+-ATPase in Saccharomyces cerevisiae adaptation and resistance to the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D)", Biochemical and Biophysical Research Communications, 312, 1317-1324, 2003 (abstract)

M.V. Cunha, J.H. Leitão, E. Mahenthiralingam, P. Vandamme, L. Lito, C. Barreto, M.J. Salgado, I. Sá-Correia, "Molecular analysis of Burkholderia cepacia complex isolates from a Portuguese cystic fibrosis center: a seven-year study", Journal of Clinical Microbiology, 41, 4113-4120, 2003 (abstract)

P. Sist, P. Cescutti ,  S. Sveerlavaj, R. Urbani,  J.H. Leitão,  I. Sá-Correia, R. Rizzo, "Macromolecular and solution properties of Cepacian: the exopolysaccharide produced by a strain of Burkholderia cepacia isolated from a cystic fibrosis patient", Carbohydrate Research, 338, 1861-1867, 2003 (abstract)

I.M. Tavares, J.H. Leitão, I. Sá-Correia , "Chromosomal organization and transcription analysis of genes in the vicinity of Pseudomonas aeruginosa glmM gene encoding phosphoglucosamine mutase", Biochemical and Biophysical Research Communications, 302, 363-371, 2003 (abstract)

A.R. Marques, P.M. Coutinho, P. Videira, A.M. Fialho, I. Sá-Correia, "Sphingomonas paucimobilis b-glucosidase Bgl1: a member of a new bacterial subfamily in family 1 of glycoside hydrolases", Biochemical Journal, 370,793-804, 2003 (abstract)

A.R.Marques, P.B. Ferreira, I.Sá-Correia, A.M. Fialho, "Characterization of the ugpG gene encoding a UDP-glucose pyrophosphorylase from the gellan gum producer Sphingomonas paucimobilis ATCC 31461", Molecular Genetics and Genomics, 268, 816-824, 2003 (abstract)

P. Videira , Fialho A.M., Marques A.R., Coutinho P.M., Sá-Correia I., "Cloning and sequence analysis of the ces 10 gene encoding a Sphingomonas paucimobilis esterase", Applied Microbiology and Biotechnology, 61, 517-522, 2003 (abstract)

A.R. Fernandes, I. Sá-Correia, "Transcription patterns of PMA1 and PMA2 genes and activity of plasma membrane H+-ATPase in Saccharomyces cerevisiae during diauxic growth and stationary phase", Yeast, 20, 207-219, 2003 (abstract)

M.G. Cabral, C.A. Viegas, M.C. Teixeira and I. Sá-Correia, "Toxicity of chlorinated phenoxyacetic acid herbicides in the experimental eukaryotic model Saccharomyces cerevisiae: role of pH and of growth phase and size of the yeast cell population", Chemosphere, 51, 47-54, 2002 (abstract)

2002

T. Felder, E. Bogengruber,  S. Tenreiro, A.Ellinger, I. Sá-Correia, P. Briza , "Dtr1p, a multidrug resistance transporter of the major facilitator superfamily, plays an essential role in spore wall maturation in Saccharomyces cerevisiae", Eukaryotic Cell, 1, 799-810, 2002 

I.Sá-Correia, A. M. Fialho,  P.Videira, L. M. Moreira , A. R. Marques, Albano H., "Gellan gum biosynthesis in Sphingomonas paucimobilis ATCC 31461: genes, enzymes and exopolysaccharide production  engineering", Journal of Industrial Microbiology and Biotechnology, 29, 170-176, 2002

I.Sá-Correia , S.Tenreiro , "The multidrug resistance transporters of the major facilitator superfamily, six years after disclosure of Saccharomyces cerevisiae genome sequence", Journal of Biotechnology, 98, 215-226, 2002

F.M.C. Santanta , T. Pinto , A.M. Fialho , I. Sá-Correia ,  J.Empis, “Bacterial removal of quinolizidine alkaloids and other carbon sources from a Lupinus albus aqueous extract”, Journal of Agricultural and Food Chemistry, 50, 2318-2323, 2002 (abstract)

S. Tenreiro,  P.A.Nunes, C.A. Viegas, M.S. Neves,  M.C. Teixeira, M.G. Cabral, I. Sá-Correia, “AQR1 gene (ORF YNL065w) encodes a plasma membrane transporter of the Major Facilitator Superfamily that confers Resistance to Short-chain Monocarboxylic Acids and Quinidine in Saccharomyces cerevisiae”, Biochemical and Biophysical Research Communications, 292, 741-748, 2002 (abstract)

M. C. Teixeira and I. Sá-Correia,  "Saccharomyces cerevisiae resistance to chlorinated phenoxyacetic acid herbicides involves Pdr1p–mediated transcriptional activation of TPO1 and PDR5 genes", Biochemical Biophysical Research Communications, 292, 530-537, 2002 (abstract)

 

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