Filipa Canaveira Roque

(PhD Student) *

Alternative Pages: Google Scholar; Research ID; iBB webpage

Status at iBB - Institute for Bioengineering and Biosciences:

·         Researcher of the Biological Sciences Research Group

Education:

  • Integrated Master in Biologial Engineering , Instituto Superior Técnico, University of Lisbon, Portugal, 2012

Positions:

  • PhD Student in Biotechnology, under the supervision of Professors Isabel Sá-Correia and Miguel Cacho Teixeira.

Research Activities:

  • Yeast Toxicogenomics -genome-wide adaptive responses and resistance to chemical compounds relevant in Industrial Biotechnology.

  • Microbial physiology and molecular biology of Saccharomyces cerevisiae and Zygosaccharomyces bailii

  • NMR-based metabolomics

Grants:

  • PhD scholarship SFRH/BD/82226/2011, granted by FCT - Fundação para a Ciência e Tecnologia

Publications:

Papers in International Journals

Palma, M., Dias, P.J., Roque, F.C., Luzia, L., Guerreiro, J.F., Sá-Correia, I., The Zygosaccharomyces bailii transcription factor Haa1 is required for acetic acid and copper stress responses suggesting subfunctionalization of the ancestral bifunctional protein Haa1/Cup2, BMC Genomics, in press.

Palma, P., Roque, F.C., Guerreiro, J., Mira, N.P., Queiroz, L., Sá-Correia, I., "Search for genes responsible for the remarkably high acetic acid tolerance of a Zygosaccharomyces bailii-derived interspecies hybrid strain", BMC Genomics, 16:1070, 2015.

Mira, N.P., Münsterkötter, M., Dias-Valada, F., Santos, J., Palma, M., Roque, F., Guerreiro, J., Rodrigues, F., Sousa, M.J., Leão, C., Guldener, U., Sá-Correia, I., "The genome sequence of the highly acetic acid-tolerant Zygosaccharomyces bailii derived interspecies hybrid strain ISA1307, isolated from a sparkling wine plant", DNA Research, 21(3):299-313, 2014.

Lourenço, A.B., Roque, F.C., Teixeira, M.C., Ascenso, J.R., Sá-Correia, I., Quantitative 1H-NMR-metabolomics reveals extensive metabolic reprogramming and the effect of the aquaglyceroporin FPS1 in ethanol-stressed yeast cells, PLOS One, 8(2): e55439, 2013.

de Kok, S., Nijkamp, J.F., Oud, B., Roque, F.C., de Ridder, D., Daran, J.M., Pronk, J.T., van Maris, A.J., Laboratory evolution of new lactate transporter genes in a jen1Δ mutant of Saccharomyces cerevisiae and their identification as ADY2 alleles by whole-genome resequencing and transcriptome analysis, FEMS Yeast Research, 12: 359–374, 2012.