Ana Sílvia Soares Mendes Moreira

(PhD Student) *

Alternative Pages: Google Scholar; Research ID; iBB webpage

Status at iBB - Institute for Bioengineering and Biosciences:

·         Researcher of the Biological Sciences Research Group

Education:

  • Graduation in Microbiology, Faculty of Medicine, University of Lisbon, Portugal, 2009

  • Master in Applied Microbiology, Faculty of Sciences, University of Lisbon, Portugal, 2012

Positions:

  • PhD Student in Biotechnology, under the supervision of Professor Isabel Sá-Correia.

Research Activities:

  • Genome-wide adaptive mechanisms used by Burkholderia cepacia complex bacteria to adapt and persist in the stressing environment of the lung of cystic fibrosis patients during long-term colonization.

Grants:

  • PhD scholarship SFRH/BD/82162/2011, granted by FCT - Fundação para a Ciência e Tecnologia

Publications:

Papers in International Journals

Moreira, A.S., Lourenço, A.B., Sá-Correia, I., 1H-NMR-based endometabolome profiles of Burkholderia cenocepacia clonal variants retrieved from a cystic fibrosis patient during chronic infection, Frontiers in Microbiology, 7:2024, 2016.

Moreira, A.S., Mil-Homens, D.*, Sousa, S.A.*, Coutinho, C.P.*, Pinto-de-Oliveira, A., Ramos, C.G., dos Santos, S.C., Fialho, A.M., Leitão, J.H., Sá-Correia, I., Variation of Burkholderia cenocepacia virulence potential during cystic fibrosis chronic lung infection. Virulence (in press).

Cullen, L., Weiser, R., Olszak, T., Maldonado, R.F., Moreira, A.S., Slachmuylders, L., Brackman, G., Paunova-Krasteva, T.S., Zarnowiec, P., Czerwonka, G., Reilly, J., Drevinek, P., Kaca, W., Melter, O., de Soyza, A., Perry, A., Winstanley, C., Stoitsova, S.R., Lavigne, R., Mahenthiralingam, E., Sá-Correia, I., Coenye, T., Drulis-Kawa, Z., Augustyniak, D., Valvano, M.A., McClean, S., "Phenotypic characterisation of an international Pseudomonas aeruginosa reference panel: Strains of cystic fibrosis origin show less in vivo virulence than non-CF strains", Microbiology, 161: 1961-1977, 2015. 

Moreira, A.S., Coutinho, C.P., Avezedo, P., Lito, L., Melo-Cristino, J., Sá-Correia, I., "Burkholderia dolosa phenotypic variation during the decline in lung function of a cystic fibrosis patient along 5.5 years of chronic colonization", Journal of Medical Microbiology, 63: 594-601, 2014.

dos Santos, S.C., Mira, N.P., Moreira, A.S., Sá-Correia, I., Quantitative- and phospho-proteomic analysis of the yeast response to the tyrosine kinase inhibitor imatinib. OMICS: A Journal of Integrative Biology, 16: 537-51.

Mira, N.P., Madeira, A., Moreira, A.S., Coutinho, A.P., Sá-Correia, I., Genomic expression analysis reveals strategies of Burkholderia cenocepacia to adapt to the airways of cystic fibrosis patients and antimicrobial therapy . PLOS One, 6(12), e28831, 2011.

Coutinho, C.P., dos Santos, S.C., Madeira, A., Mira, N.P., Moreira, A.S., Sá-Correia, I., Long-term colonization of the cystic fibrosis lung by Burkholderia cepacia complex bacteria: epidemiology, clonal variation and genome-wide expression alterations. Frontiers in Cellular and Infection Microbiology, 1, 12, 2011.